Inria Associate Team ALEGRIA
Coordinator: (France) ERABLE Team, Inria and (Brazil) Instituto de Biologia Molecular do Paraná – Fiocruz-PR, Paraná.
Parasitic protists include agents of human and animal diseases that have a huge impact on world populations and economy. The major public health problems of protozoan organisms come mainly from the phylum Apicomplexa or the Class Kinetoplastida (from the phylum Euglenozoa).
An important subject yet largely under-explored is the fact that most members from these groups are pathogenic while a small fraction is not, which raises the question of what gives origin to the pathogenicity of these parasites. This is the main question we wish to address by means of computational methods and wet-lab experiments.