Directrice de recherche, Inria

Contact information

• Address:

Office A321
Centre de Recherche Inria de Paris
2 rue Simone Iff
CS 42112
75589 Paris Cedex 12 (FRANCE)

• e-mail: irene.vignon-clementel at inria.fr
• phone: +33.1.80.49.42.67
• https://team.inria.fr/reo/team-members/irene-vignon-clementel/

Publications

• 6 main publications to download
• List of main publications
• Link to google scholar search

Scientific interests

• Mathematical Modeling and Numerical Methods
  • boundary conditions for physiological fluid dynamics (3D,1D)
  • multi-domain modeling & numerical methods for their coupling
  • model parametrization from real data (multi-level approach, data assimilation)

• Modeling and inverse problem for dynamic imaging interpretation (DCE-US, DCE-MRI, …, ICG fluorescence)
• Applications
  • congenital heart disease (single ventricle, ToF) & acquired disease (aneurysms, stenosis, etc)
  • treatment planning (Fontan surgeries, percutaneous valve reducer, liver surgery)
  • coronary circulation
  • airflow and particle deposition in health and disease
  • oncology application: interaction between vascularization & tumor development

Students

PhD students (formal)

• Omar Ali (2020-), U. Paris-Saclay (coadvisor: E Vibert )
• Nicolas Golse (expected 2020), PhD student in medicine (ED de Cancérologie 582, coadvisors: E Vibert and S Cottin) Apports de la modélisation anatomique et hémodynamique du foie dans l’anticipation, la réalisation et l’enseignement de la chirurgie hépatique.
• Noémie Boissier (2018), Sorbonne U. (coadvisor: D Drasdo) Blood perfusion modeling in tumors and liver. 
• Nicolas Pozin (2017), Sorbonne U. (coadvisor: C Grandmont) Multiscale lung ventilation modeling in health and disease. 
• Chloé Audebert (2017), Sorbonne U. (coadvisor: JF Gerbeau) Mathematical liver modelling: hemodynamics and function in hepatectomy. Prix de thèse AMIES 2018
• Gregory Arbia (2014), Sorbonne U. (coadvisor: JF Gerbeau) Multiscale modeling of blood flow applied to congenital heart disease. Now at Sorin group.

PhD students (informal)

• Florian Joly (2019), PhD student at U. Montreal, Canada. Advisors: C Kauffmann, G Soulez. Numerical Insights for AAA Growth Understanding and Predicting: Morphological and Hemodynamic Risk Assessment Features and Transient Coherent Structures Uncovering. Now postdoc in Inserm.
• Stephanie Lindsey (2015), PhD student at Cornell University, USA. Advisor:  J Butcher.  Hemodynamic regulation of cardiac outflow morphogenesis. Now postdoc at Stanford U.
• Mahdi Esmaily-Moghadam (2014), PhD student at UCSD, USA. Supervisor: A. Marsden. Development of multiscale modeling methods for clinical decision making in single ventricle heart patients. Now assistant professor at Cornell University, USA.
• Jessica Oakes (2013), PhD student at UCSD, USA. Supervisors: C Darquenne (School of Medicine) and A. Marsden (School of Engineering). Aerosol Deposition in Healthy and Emphysematous Rat Lungs: Insights From MRI Measurements and Computational Simulations. Now Assistant Professor at Northeastern U., USA.
• Weiguang Yang (2012), PhD student at UCSD, USA. Supervisor: A. Marsden. Surgical design for the Fontan procedure using computational fluid dynamics and derivative-free optimization. Now research fellow at Stanford U.
• Nick Jagiella (2012), PhD student at UPMC/U. of Leipzig. Supervisor: D Drasdo. Parametrisation of lattice-based tumor models from data. Now at Advanced RealTime Tracking Gmbh.
• Rashmi Raghu (2011), PhD student at Stanford University, USA of C Taylor. Computational models of blood flow in deformable arteries including viscoelasticity. Now at Pivotal Inc.
• H.J. Kim (2009), PhD student at Stanford University, USA of C Taylor.  3D finite-element modeling of blood flow in the coronary arteries. Now at Heartflow.

Editorial activity

• International Journal for Numerical Methods in Biomedical Engineering, Wiley (associate editor, since 2018)

Grants and Awards

• ERC consolidator grant (2020-2025)
• iLite, RHU (2017-2021, INRIA PI Dirk Drasdo)
• iFLOW, ANR Tecsan (2013-2017)
• Transatlantic Leducq grant – a Trans-Atlantic Network of Excellence for Cardiovascular Research, (2010-2016):  Multi-scale Modeling of Single Ventricle Hearts for Clinical Decision Support

• Grant to organize the 4^th International Conference on Engineering Frontiers in Pediatric and Congenital Heart Disease,  France-Stanford Center fund, (2013-2014)
• CARDIO – Equipe associée / Associated team grant from INRIA (with Stanford University & associated colleagues), (2008-2013)
• Grant, France-Stanford Center fund, (2007-2008)
• Award for the Student Presentation Competition in the Biotechnology Specialty area at the World Congress of Computational Mechanics by the USACM and the USACM Executive Committee (Aug. 2006)
• Dean’s Postdoctoral Fellowship, Stanford School of Medicine (awarded in 2006)
• Predoctoral Fellowship, American Heart Association (Top recipient of the Western States, USA ; 2004-2006)
• 2nd prize of the student competition research presentation, BCATS conference, Stanford, Nov 2005
• Cambridge European Trust bursary (1999-2000)
• Scholarship from the Ecole Centrale Paris for the international program TimePlus (1999-2000)

Education

• HDR (Habilitation à diriger des recherches), Ecole Doctorale de Sciences Mathématiques Paris Centre, Université Pierre et Marie Curie, Paris, France – 2016.
• PhD, Department of Mechanical Engineering, Stanford University, USA, thesis under the supervision of Prof. Charles A. Taylor in the Cardiovascular Biomedical Research Laboratory (download PhD_thesis) – 2006
• MS (Part III), Department of Applied Mathematics and Theoretical Physics, University of Cambridge, UK – thesis under the supervision of Prof. Timothy Pedley in the Biological Mechanics Group – 2000
• Diplome d’ingénieur, Ecole Centrale Paris, France – 2000