Brigitte Sabatier


Brigitte Sabatier
Pharmacist,
Hospital practitioner,
AP-HP
email: first name dot last name at aphp dot fr
postal address: , Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc, 75015 Paris
bio: I’m a pharmacist, hospital practitioner, working in Georges Pompidou european Hospital. I’m responsible of medication process unit.

Research projects

We are working on data routinely collected from the Hospital Information System for research purposes to improve patient safety through the care pathway and more specifically the medication process. Our research evaluates knowledge-driven and data-driven approaches in terms of errors or even morbidity and mortality avoided for the patient. These approaches are implemented at different steps of the medication process: prescribing, pharmaceutical analysis of prescriptions and drug administration. The conceptualization, selection and evaluation of these clinical decision rule based alerts are based on the use of patient-specific data (clinic including age and sex, biological, drug history, adherence) and drug data to optimize therapeutic protocols and quality of care. Our current prospects are to look for tools whose approach is based on data mining to detect a link between drug and pathology and to evaluate them though routine care data (with the clinical data warehouse of the Georges Pompidou European hospital) and administrative data of the National Health Data System (SNDS).


Publications

Publications HAL de brigitte, sabatier

2024

Conference papers

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Jong Ho Jhee, Alice Rogier, Dune Giraud, Emma Pinet, Brigitte Sabatier, et al.. Representation and comparison of chemotherapy protocols with ChemoKG and graph embeddings. SWAT4HCLS 2024 – 15th International Semantic Web Applications and Tools for Health Care and Life Sciences Conferenc, Feb 2024, Leiden (NL), Netherlands. ⟨hal-04455155⟩
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https://hal.science/hal-04455155/file/manuscript_ChemoKG_camera-ready.pdf BibTex

2023

Journal articles

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Emmanuelle Gras, Yohann Tran, Benjamin Kably, Agnès Lillo-Lelouet, Thibaut Caruba, et al.. Prospective assessment of the frequency of and risk factors for bleeding events in patients treated with cefazolin. Infection, In press, ⟨10.1007/s15010-023-02145-1⟩. ⟨hal-04432550⟩
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https://hal.sorbonne-universite.fr/hal-04432550/file/Manuscript%20HAL.pdf BibTex
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Marc Sapoval, Charles Querub, Helena Pereira, Olivier Pellerin, Tom Boeken, et al.. Genicular artery embolization for knee osteoarthritis: Results of the LipioJoint-1 trial. Diagnostic and Interventional Imaging, 2023, ⟨10.1016/j.diii.2023.12.003⟩. ⟨hal-04349672⟩
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Virginie Korb-Savoldelli, Yohann Tran, Germain Perrin, Justine Touchard, Jean Pastre, et al.. Psychometric Properties of a Machine Learning–Based Patient-Reported Outcome Measure on Medication Adherence: Single-Center, Cross-Sectional, Observational Study. Journal of Medical Internet Research, 2023, 25, pp.e42384. ⟨10.2196/42384⟩. ⟨hal-04343657v2⟩
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Marc Sapoval, Nicolas Thiounn, Aurélien Descazeaud, Carole Déan, Alain Ruffion, et al.. Prostatic artery embolisation versus medical treatment in patients with benign prostatic hyperplasia (PARTEM): a randomised, multicentre, open-label, phase 3, superiority trial. The Lancet Regional Health – Europe, 2023, 31, pp.100672. ⟨10.1016/j.lanepe.2023.100672⟩. ⟨hal-04199136⟩
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https://univ-rennes.hal.science/hal-04199136/file/1-s2.0-S2666776223000911-main.pdf BibTex
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Tess Martin, Alessandra Guercio, Hélène Besseau, Laure Huot, Pascale Guerre, et al.. Hospital-based health technology assessment of innovative medical devices: insights from a nationwide survey in France. International Journal of Technology Assessment in Health Care, 2023, 39 (1), ⟨10.1017/S0266462323000521⟩. ⟨hal-04229548⟩
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https://hal.science/hal-04229548/file/2023_Borget_IntJTechnolAssessHealthCare_MAA.pdf BibTex

2022

Journal articles

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Thibaut Caruba, Anaïs Charles-Nelson, John Alexander, Rajendra Mehta, Matthias Heringlake, et al.. Prophylactic levosimendan in patients with low ejection fraction undergoing coronary artery bypass grafting: A pooled analysis of two multicentre randomised controlled trials. Anaesthesia Critical Care & Pain Medicine, 2022, 41 (4), pp.101107. ⟨10.1016/j.accpm.2022.101107⟩. ⟨hal-03794008⟩
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Emma Pinet, Pierre Sabatier, Marie-Paule Fernandez-Gerlinger, Anne-Sophie Jannot, Jean-Luc Mainardi, et al.. Impact of medical and pharmaceutical interventions on anti-infective prescriptions: an observational study. European Journal of Clinical Microbiology and Infectious Diseases, 2022, 41 (7), pp.1077-1086. ⟨10.1007/s10096-022-04465-w⟩. ⟨hal-03794006⟩
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Cyril Baudrier, Yohann Tran, Nicolas Delanoy, Sandrine Katsahian, Brigitte Sabatier, et al.. Identifying homogeneous healthcare use profiles and treatment sequences by combining sequence pattern mining with care trajectory clustering in kidney cancer patients on oral anticancer drugs: A case study. Health Informatics Journal, 2022, 28 (2), pp.146045822211015. ⟨10.1177/14604582221101526⟩. ⟨hal-03794007⟩
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Xavier Mariette, Olivier Hermine, Pierre-Louis Tharaux, Matthieu Resche-Rigon, Raphael Porcher, et al.. Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial. The Lancet Rheumatology, 2022, 4 (1), pp.e24-e32. ⟨10.1016/S2665-9913(21)00315-5⟩. ⟨hal-04399070⟩
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Xavier Mariette, Olivier Hermine, Pierre-Louis Tharaux, Matthieu Resche-Rigon, Raphael Porcher, et al.. Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial. The Lancet Rheumatology, 2022, 4 (1), pp.e24-e32. ⟨10.1016/S2665-9913(21)00315-5⟩. ⟨hal-03783213⟩
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Germain Perrin, Armelle Arnoux, Sarah Berdot, Sandrine Katsahian, Nicolas Danchin, et al.. Association Between Exposure to Effervescent Paracetamol and Hospitalization for Acute Heart Failure: A Case-Crossover Study. Journal of Clinical Pharmacology, 2022, 62 (7), pp.883-890. ⟨10.1002/jcph.2027⟩. ⟨hal-03644630⟩
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https://hal.sorbonne-universite.fr/hal-03644630/file/TheJournalofClinicalPharma-2022-Perrin-AssociationBetweenExposuretoEffervescentParacetamoland%20%281%29.pdf BibTex

2021

Journal articles

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Sarah Berdot, Aurélie Vilfaillot, Yvonnick Bezie, Germain Perrin, Marion Berge, et al.. Effectiveness of a ‘do not interrupt’ vest intervention to reduce medication errors during medication administration: a multicenter cluster randomized controlled trial. BMC Nursing, 2021, 20 (1), pp.153. ⟨10.1186/s12912-021-00671-7⟩. ⟨inserm-03331021⟩
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https://inserm.hal.science/inserm-03331021/file/s12912-021-00671-7.pdf BibTex
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Célia Lachuer, Germain Perrin, Aymeric Chastel, Hail Aboudagga, Constance Thibault, et al.. Pharmaceutical consultation to detect drug interactions in patients treated with oral chemotherapies: A descriptive cross‐sectional study. European Journal of Cancer Care, 2021, 30 (3), ⟨10.1111/ecc.13396⟩. ⟨hal-03349595⟩
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Adrien Coulet, Stéphanie Allassonniere, François Angoulvant, Anita Burgun, Xiaoyi Chen, et al.. L’équipe-projet HeKA. Bulletin de l’Association Française pour l’Intelligence Artificielle, 2021, 112, pp.29-32. ⟨hal-03485904⟩
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https://inria.hal.science/hal-03485904/file/equipe-projet_heka.pdf BibTex
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Germain Perrin, Christine Le Beller, Luc Darnige, Lina Khider, David Smadja, et al.. Intramuscular Vaccination in Adults with Therapeutic Anticoagulation in the Era of COVID-19 Vaccines Outbreak: A Practical Review. TH Open : Companion Journal To Thrombosis and Haemostasis, 2021, 05 (02), pp.e166-e170. ⟨10.1055/s-0041-1729627⟩. ⟨hal-03349600⟩
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Pierre-Louis Tharaux, Gilles Pialoux, Arthur Pavot, Xavier Mariette, Olivier Hermine, et al.. Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial. The Lancet Respiratory Medicine, 2021, 9 (3), pp.295-304. ⟨10.1016/S2213-2600(20)30556-7⟩. ⟨hal-03579180⟩
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Justine Touchard, Germain Perrin, Sarah Berdot, Jacques Pouchot, Marie-Caroline Loustalot, et al.. Effects of a multifaceted intervention to promote the use of intravenous iron sucrose complex instead of ferric carboxymaltose in patients admitted for more than 24 h. European Journal of Clinical Pharmacology, 2021, 77 (2), pp.189-195. ⟨10.1007/s00228-020-02993-y⟩. ⟨hal-03335341⟩
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Olivier Hermine, Xavier Mariette, Pierre-Louis Tharaux, Matthieu Resche-Rigon, Raphaël Porcher, et al.. Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia. JAMA Internal Medicine, 2021, 181 (1), pp.32-40. ⟨10.1001/jamainternmed.2020.6820⟩. ⟨hal-03579175⟩
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2020

Journal articles

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Rémi Pieragostini, Germain Perrin, Camille Nevoret, Laurence Amar, Anne‐sophie Jannot, et al.. Conditional prescriptions of oral antihypertensive drugs for the management of hypertension urgencies in the inpatient setting: An observational study. Journal of Clinical Pharmacy and Therapeutics, 2020, 45 (2), pp.282-289. ⟨10.1111/jcpt.13059⟩. ⟨hal-03349581⟩
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Rémi Pieragostini, Germain Perrin, Camille Nevoret, Laurence Amar, Anne‐sophie Jannot, et al.. Conditional prescriptions of oral antihypertensive drugs for the management of hypertension urgencies in the inpatient setting: An observational study. Journal of Clinical Pharmacy and Therapeutics, 2020, 45 (2), pp.282-289. ⟨10.1111/jcpt.13059⟩. ⟨hal-03794019⟩
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2019

Journal articles

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Sarah Berdot, Abdelali Boussadi, Aurélie Vilfaillot, Mathieu Depoisson, Claudine Guihaire, et al.. Integration of a Commercial Barcode-Assisted Medication Dispensing System in a Teaching Hospital. Applied Clinical Informatics, 2019, 10 (04), pp.615-624. ⟨10.1055/s-0039-1694749⟩. ⟨hal-03335331⟩
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Sarah Berdot, Abdelali Boussadi, Aurélie Vilfaillot, Mathieu Depoisson, Claudine Guihaire, et al.. Integration of a Commercial Barcode-Assisted Medication Dispensing System in a Teaching Hospital. Applied Clinical Informatics, 2019, 10 (04), pp.615-624. ⟨10.1055/s-0039-1694749⟩. ⟨hal-03794023⟩
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Camille Schwab, Patrick Hindlet, Brigitte Sabatier, Christine Fernandez, Virginie Korb-Savoldelli. Risk scores identifying elderly inpatients at risk of 30-day unplanned readmission and accident and emergency department visit: a systematic review. BMJ Open, 2019, 9 (7), pp.e028302. ⟨10.1136/bmjopen-2018-028302⟩. ⟨hal-02309630⟩
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https://hal.sorbonne-universite.fr/hal-02309630/file/e028302.full.pdf BibTex
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Sarah Berdot, Cécile Blanc, Delphine Chevalier, Yvonnick Bezie, Laetitia Minh Maï Lê, et al.. Impact of drug storage systems: a quasi-experimental study with and without an automated-drug dispensing cabinet. International Journal for Quality in Health Care, 2019, 31 (3), pp.225-230. ⟨10.1093/intqhc/mzy155⟩. ⟨hal-03335327⟩
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https://hal.science/hal-03335327/file/Armoires_ISQUA%202018.pdf BibTex
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Sarah Berdot, Virginie Korb-Savoldelli, Emmanuel Jaccoulet, Vincent Zaugg, Patrice Prognon, et al.. A centralized automated-dispensing system in a French teaching hospital: return on investment and quality improvement. International Journal for Quality in Health Care, 2019, 31 (3), pp.219-224. ⟨10.1093/intqhc/mzy152⟩. ⟨hal-03335338⟩
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https://hal.science/hal-03335338/file/Robot_IJQHC2018.pdf BibTex
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Marie-Caroline Loustalot, Sarah Berdot, Pierre Sabatier, Pierre Durieux, Germain Perrin, et al.. The impact of interventions by pharmacists collected in a computerised physician order entry context: a prospective observational study with a 10-year reassessment. Swiss Medical Weekly, 2019, ⟨10.4414/smw.2019.20015⟩. ⟨hal-03335354⟩
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https://hal.science/hal-03335354/file/The_impact_of_interventions_by_pharmacists_collect.pdf BibTex
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Marie-Caroline Loustalot, Sarah Berdot, Pierre Sabatier, Pierre Durieux, Germain Perrin, et al.. The impact of interventions by pharmacists collected in a computerised physician order entry context: a prospective observational study with a 10-year reassessment. Swiss Medical Weekly, 2019, ⟨10.4414/smw.2019.20015⟩. ⟨hal-03349558⟩
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Marie-Caroline Loustalot, Sarah Berdot, Pierre Sabatier, Pierre Durieux, Germain Perrin, et al.. The impact of interventions by pharmacists collected in a computerised physician order entry context: a prospective observational study with a 10-year reassessment. Swiss Medical Weekly, 2019, ⟨10.4414/smw.2019.20015⟩. ⟨hal-03794025⟩
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2018

Journal articles

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Johanne Daupin, Germain Perrin, Chloe Lhermitte-Pastor, Marie-Caroline Loustalot, Simon Pernot, et al.. Pharmaceutical interventions to improve safety of chemotherapy-treated cancer patients: A cross-sectional study. Journal of Oncology Pharmacy Practice, 2018, 25 (5), pp.1195-1203. ⟨10.1177/1078155219826344⟩. ⟨hal-03349547⟩
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Germain Perrin, Sarah Berdot, Frédérique Thomas, Bruno Pannier, Nicolas Danchin, et al.. Evaluation of exposure to effervescent drugs in a large health check-up population in France: a cross-sectional study. BMJ Open, 2018, 8 (7), pp.e022368. ⟨10.1136/bmjopen-2018-022368⟩. ⟨hal-03335364⟩
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https://hal.science/hal-03335364/file/Perrin2018.pdf BibTex
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Germain Perrin, Sarah Berdot, Frédérique Thomas, Bruno Pannier, Nicolas Danchin, et al.. Evaluation of exposure to effervescent drugs in a large health check-up population in France: a cross-sectional study. BMJ Open, 2018, 8 (7), pp.e022368. ⟨10.1136/bmjopen-2018-022368⟩. ⟨hal-03349541⟩
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Sarah Berdot, Brigitte Sabatier. Medication errors may be reduced by double-checking method. Evidence-Based Nursing, 2018, 21 (3), pp.67-67. ⟨10.1136/eb-2018-102901⟩. ⟨hal-03335317⟩
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https://hal.science/hal-03335317/file/Berdot%20double%20check%202018.full.pdf BibTex
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Camille Schwab, Alexis Le Moigne, Christine Fernandez, Pierre Durieux, Brigitte Sabatier, et al.. External validation of the 80+ score and comparison with three clinical scores identifying patients at least 75 years old at risk of unplanned readmission within 30 days after discharge. Swiss Medical Weekly, 2018, pp.148:w14624. ⟨10.4414/smw.2018.14624⟩. ⟨hal-03922560⟩
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2017

Journal articles

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Germain Perrin, Virginie Korb-Savoldelli, Alexandre Karras, Nicolas Danchin, Pierre Durieux, et al.. Cardiovascular risk associated with high sodium-containing drugs: A systematic review. PLoS ONE, 2017, 12 (7), pp.e0180634. ⟨10.1371/journal.pone.0180634⟩. ⟨hal-03349535⟩
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2014

Journal articles

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Thibaut Caruba, Sandrine Katsahian, Catherine Schramm, Anaïs Charles Nelson, Pierre Durieux, et al.. Treatment for Stable Coronary Artery Disease: A Network Meta-Analysis of Cost-Effectiveness Studies. PLoS ONE, 2014, 9 (6), pp.e98371. ⟨10.1371/journal.pone.0098371⟩. ⟨hal-03931948⟩
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https://hal.science/hal-03931948/file/file.pdf BibTex

2012

Journal articles

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Sarah Berdot, Brigitte Sabatier, Florence Gillaizeau, Thibaut Caruba, Patrice Prognon, et al.. Evaluation of drug administration errors in a teaching hospital.. BMC Health Services Research, 2012, 12 (1), pp.60. ⟨10.1186/1472-6963-12-60⟩. ⟨inserm-00702628⟩
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2010

Journal articles

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Thibaut Caruba, Isabelle Colombet, Florence Gillaizeau, Vanida Bruni, Virginie Korb, et al.. Chronology of prescribing error during the hospital stay and prediction of pharmacist’s alerts overriding: a prospective analysis.. BMC Health Services Research, 2010, 10 (1), pp.13. ⟨10.1186/1472-6963-10-13⟩. ⟨inserm-00663911⟩
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2008

Journal articles

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Abdelali Boussadi, Cedric Bousquet, Brigitte Sabatier, Isabelle Colombet, Patrice Degoulet. Specification of business rules for the development of hospital alarm system: application to the pharmaceutical validation.. Studies in Health Technology and Informatics, 2008, 136, pp.145-50. ⟨hal-00337200⟩
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1993

Poster communications

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Stéphane Gibaud, Gabrielle Gennaro, Nicolas Brassier, Brigitte Sabatier, Marie-Laure Hugues, et al.. Mise au point du dosage du glutaraldéhyde résiduel après le nettoyage et la désinfection des endoscopes du service d’endoscopie digestive de l’hôpital Broussais.. Vèmes journées franco-suisses, Oct 1993, Beaune (France), France. ⟨hal-04042189⟩
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