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tissueMORPH
- tissueMORPH is a software that permits 2D agent-based simulations of tissue morphogenesis and regeneration/wound healing. Simulation platform enabling to perform simulations of systems composed of individual cells (disks) growing and interacting in a dynamical fiber network (composed of cross-linked fibers – segments). The platform enables to explore the mechanisms of tissue construction (morphogenesis) and tissue reparation after injury (regeneration/wound healing) . The software includes many modules specifically tailored to support the simulation and analysis of virtual tissues including 2D visualization and image processing tools. Cell and fiber network parameters can be independently varied which facilitates specific simulations and allows for detailed analyses of growth dynamics and links between matrix mechanical properties and tissue construction/reconstruction. Applications: adipose tissues morphogenesis, tissue reparation, wound healing, muscles, dynamical fiber networks.
- Diane Peurichard (diane.a.peurichard@inria.fr)
- Diane Peurichard (diane.a.peurichard@inria.fr), Pauline Chassonnery (pauline.chassonnery@inria.fr), Louis Casteilla (louis.casteilla@inserm.fr), Pierre Degond (pierre.degond@math.univ-tlse.fr), Anastasia Pacary (anastasia.pacary@inserm.fr), Jenny Paupert (jenny.paupert@inserm.fr)
- MAMBA, MUSCLEES