Moreno Ursino


Moreno Ursino
email : moreno.ursino@inria.fr
adresse postale : Université de Paris – Site Villemin, 10 avenue de Verdun, 75010, Paris.
site internet : www.morenoursino.com
bio : Je suis CR Inserm,; ingénieur mathématicien (une façon très agréable de dire « mathématicien appliqué ») avec un doctorat en biostatistique.

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Publications

Publications HAL de Moreno Ursino

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Criteria : Author : « Moreno Ursino »
Number of occurrences founded : 47.

titre
Survival without severe neonatal morbidity after antenatal betamethasone dose reduction: a post hoc analysis of a randomized non-inferiority trial
auteur
Olivier Baud, Moreno Ursino, Loic Sentilhes, Muriel Doret-Dion, Corinne Alberti, Camille Aupiais, Thomas Schmitz
article
American Journal of Obstetrics and Gynecology, 2024, Online ahead of print. ⟨10.1016/j.ajog.2024.02.002⟩
titre
A Seamless hybrid Phase II/III design with Bayesian interim subgroup selection
auteur
Benjamin Duputel, Nigel Stallard, François Montestruc, Sarah Zohar, Moreno Ursino
article
2024
titre
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network
auteur
Claire Dupuis, Etienne de Montmollin, Niccolò Buetti, Dany Goldgran-Toledano, Jean Reignier, Carole Schwebel, Julien Domitile, Mathilde Neuville, Moreno Ursino, Shidasp Siami, Stéphane Ruckly, Corinne Alberti, Bruno Mourvillier, Sebastien Bailly, Virginie Laurent, Marc Gainnier, Bertrand Souweine, Jean-François Timsit
article
PLoS ONE, 2021, 16 (8), pp.e0255644. ⟨10.1371/journal.pone.0255644⟩
titre
A straightforward meta‐analysis approach for oncology phase I dose‐finding studies
auteur
Christian Röver, Moreno Ursino, Tim Friede, Sarah Zohar
article
Statistics in Medicine, 2022, 41 (20), pp.3915-3940. ⟨10.1002/sim.9484⟩
titre
Estimating Similarity of Dose–Response Relationships in Phase I Clinical Trials—Case Study in Bridging Data Package
auteur
Adrien Ollier, Sarah Zohar, Satoshi Morita, Moreno Ursino
article
International Journal of Environmental Research and Public Health, 2021, 18 (4), pp.1639. ⟨10.3390/ijerph18041639⟩
titre
Bayesian variable selection based on clinical relevance weights in small sample studies—Application to colon cancer
auteur
Sandrine Boulet, Moreno Ursino, Peter F Thall, Anne-Sophie Jannot, Sarah Zohar
article
Statistics in Medicine, 2019, 38 (12), pp.2228-2247. ⟨10.1002/sim.8107⟩
titre
Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance
auteur
Christina Yap, Olga Solovyeva, Johann de Bono, Jan Rekowski, Dhrusti Patel, Thomas Jaki, Adrian Mander, Thomas Evans, Richard Peck, Kathryn Hayward, Sally Hopewell, Moreno Ursino, Khadija Rerhou Rantell, Melanie Calvert, Shing Lee, Andrew Kightley, Deborah Ashby, An-Wen Chan, Elizabeth Garrett-Mayer, John Isaacs, Robert Golub, Olga Kholmanskikh, Dawn Richards, Oliver Boix, James Matcham, Lesley Seymour, S Percy Ivy, Lynley Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan Berlin, Aude Espinasse, Munyaradzi Dimairo, Christopher Weir
article
BMJ – British Medical Journal, In press, pp.e076387. ⟨10.1136/bmj-2023-076387⟩
titre
Coping with Information Loss and the Use of Auxiliary Sources of Data: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions
auteur
Silvia Calderazzo, Sergey Tarima, Carissa Reid, Nancy Flournoy, Tim Friede, Nancy Geller, James Rosenberger, Nigel Stallard, Moreno Ursino, Marc Vandemeulebroecke, Kelly van Lancker, Sarah Zohar
article
Statistics in Biopharmaceutical Research, 2023, pp.1-17. ⟨10.1080/19466315.2023.2211023⟩
titre
A new parsimonious model for ordinal longitudinal data with application to subjective evaluations of a gastrointestinal disease
auteur
Moreno Ursino, Mauro Gasparini
article
Statistical Methods in Medical Research, 2018, 27 (5), pp.1376-1393. ⟨10.1177/0962280216661370⟩
titre
Levetiracetam optimal dose-finding as first-line treatment for neonatal seizures occurring in the context of hypoxic-ischaemic encephalopathy (LEVNEONAT-1) study protocol of a phase II trial
auteur
Géraldine Favrais, Moreno Ursino, Catherine Mouchel, Estelle Boivin, Vincent Jullien, Sarah Zohar, Elie Saliba
article
BMJ Open, 2019, 9 (1), pp.e022739. ⟨10.1136/bmjopen-2018-022739⟩
titre
Full versus half dose of antenatal betamethasone to prevent severe neonatal respiratory distress syndrome associated with preterm birth: study protocol for a randomised, multicenter, double blind, placebo-controlled, non-inferiority trial (BETADOSE)
auteur
Thomas Schmitz, Corinne Alberti, Moreno Ursino, Olivier Baud, Camille Aupiais
article
BMC Pregnancy and Childbirth, 2019, 19, pp.67. ⟨10.1186/s12884-019-2206-x⟩
titre
Nissen fundoplication and dyspeptic symptoms: is the water load test useful?
auteur
Edda Battaglia, Valentina Boano, Moreno Ursino, Chiara Elia, Luigi Russo, Carlo Sguazzini, Mauro Gasparini, Mario Grassini
article
Minerva Gastroenterologica e Dietologica, 2020, 66 (1), ⟨10.23736/S1121-421X.19.02632-1⟩
titre
Dose-finding designs for cumulative toxicities using multiple constraints
auteur
Shing Lee, Moreno Ursino, Ying Kuen Cheung, Sarah Zohar
article
Biostatistics, 2019, 20 (1), pp.17-29. ⟨10.1093/biostatistics/kxx059⟩
titre
Random-effects meta-analysis of Phase I dose-finding studies using stochastic process priors
auteur
Moreno Ursino, Christian Röver, Sarah Zohar, Tim Friede
article
Annals of Applied Statistics, 2021, 15 (1), ⟨10.1214/20-AOAS1390⟩
titre
Bayesian modeling of a bivariate toxicity outcome for early phase oncology trials evaluating dose regimens
auteur
Emma Gerard, Sarah Zohar, Christelle Lorenzato, Moreno Ursino, Marie‐karelle Riviere
article
Statistics in Medicine, 2021, ⟨10.1002/sim.9113⟩
titre
Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance
auteur
Christina Yap, Jan Rekowski, Moreno Ursino, Olga Solovyeva, Dhrusti Patel, Munyaradzi Dimairo, Christopher Weir, An-Wen Chan, Thomas Jaki, Adrian Mander, Thomas Evans, Richard Peck, Kathryn Hayward, Melanie Calvert, Khadija Rerhou Rantell, Shing Lee, Andrew Kightley, Sally Hopewell, Deborah Ashby, Elizabeth Garrett-Mayer, John Isaacs, Robert Golub, Olga Kholmanskikh, Dawn Richards, Oliver Boix, James Matcham, Lesley Seymour, S Percy Ivy, Lynley Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan Berlin, Aude Espinasse, Johann de Bono
article
BMJ – British Medical Journal, In press, pp.e076386. ⟨10.1136/bmj-2023-076386⟩
titre
Bayesian treatment comparison using parametric mixture priors computed from elicited histograms
auteur
Peter Thall, Moreno Ursino, Véronique Baudouin, Corinne Alberti, Sarah Zohar
article
Statistical Methods in Medical Research, 2019, 28 (2), pp.404-418. ⟨10.1177/0962280217726803⟩
titre
Recent advances in methodology for clinical trials in small populations the InSPiRe project
auteur
Tim Friede, Martin Posch, Sarah Zohar, Corinne Alberti, Norbert Benda, Emmanuelle Comets, Simon Day, Alex Dmitrienko, Alexandra Graf, Burak Kuersad Guenhan, Siew Wan Hee, Frederike Lentz, Jason Madan, Frank Miller, Thomas Ondra, Michael Pearce, Christian Roever, Artemis Toumazi, Steffen Unkel, Moreno Ursino, Gernot Wassmer, Nigel Stallard
article
Orphanet Journal of Rare Diseases, 2018, 13 (1), pp.186. ⟨10.1186/s13023-018-0919-y⟩
titre
Meta-analysis of phase I dose-finding studies: Application for protein kinase inhibitors developed in oncology
auteur
Laura Caquelin, P. Badra, Moreno Ursino, Bruno Laviolle, Clara Locher
article
EPICLIN 2023 17e Conférence francophone d’Épidémiologie Clinique – 30e Journées des statisticiens des Centres de Lutte contre le Cancer, May 2023, Villers-lès-Nancy, France. ⟨10.1016/j.respe.2023.101816⟩
titre
Bayesian modeling of a bivariate toxicity outcome for early phase oncology trials evaluating dose regimens
auteur
Emma Gerard, Sarah Zohar, Christelle Lorenzato, Moreno Ursino, Marie‐karelle Riviere
article
Statistics in Medicine, 2021, ⟨10.1002/sim.9113⟩
titre
The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia
auteur
Robin Michelet, Moreno Ursino, Sandrine Boulet, Sebastian Franck, Fiordiligie Casilag, Mara Baldry, Jens Rolff, Madelé van Dyk, Sebastian Wicha, Jean-Claude Sirard, Emmanuelle Comets, Sarah Zohar, Charlotte Kloft
article
Pharmaceutics, 2021, 13 (5), pp.601. ⟨10.3390/pharmaceutics13050601⟩
titre
Bayesian treatment comparison using parametric mixture priors computed from elicited histograms
auteur
Peter F Thall, Moreno Ursino, Véronique Baudouin, Corinne Alberti, Sarah Zohar
article
Statistical Methods in Medical Research, 2017, 28 (2), pp.404-418. ⟨10.1177/0962280217726803⟩
titre
Neonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial
auteur
Thomas Schmitz, Muriel Doret-Dion, Loic Sentilhes, Olivier Parant, Olivier Claris, Laurent Renesme, Julie Abbal, Aude Girault, Héloïse Torchin, Marie Houllier, Nolwenn Le Saché, Alexandre Vivanti, Daniele de Luca, Norbert Winer, Cyril Flamant, Claire Thuillier, Pascal Boileau, Julie Blanc, Véronique Brevaut, Pierre-Emmanuel Bouet, Géraldine Gascoin, Gaël Beucher, Valérie Datin-Dorriere, Stéphane Bounan, Pascal Bolot, Christophe Poncelet, Corinne Alberti, Moreno Ursino, Camille Aupiais, Olivier Baud, Philippe Boize, Charles Garabédian, Florence Flamein, Maela Le Lous, Alain Beuchée, Jean Gondry, Pierre Tourneux, Perrine Coste-Mazeau, Antoine Bedu, Denis Gallot, Karen Coste, Céline Chauleur, Hugues Patural, Gilles Kayem, Delphine Mitanchez, Hélène Heckenroth, Farid Boubred, Jeanne Sibiude, Luc Desfrère, Caroline Bohec, Thierry Mansir, Antoine Koch, Pierre Kuhn, Nadia Tillouche, Fabrice Lapeyre, Franck Perrotin, Géraldine Favrais, Edouard Lecarpentier, Xaxier Durrmeyer, Véronique Equy, Thierry Debillon, Luc Rigonnot, Stéphanie Lefoulgoc, Claudia Brie, Anne-Sophie Pagès, Romy Rayssiguier, Gilles Cambonie, Corinne Cudeville, Doriane Madeleneau, Olivier Morel, Jean-Michel Hascoet, Vincent Letouzey, Massimo Di Maio, Laurent Salomon, Alexandre Lapillonne
article
The Lancet, 2022, 400 (10352), pp.592-604. ⟨10.1016/S0140-6736(22)01535-5⟩
titre
Conditional Non-parametric Bootstrap for Non-linear Mixed Effect Models
auteur
Emmanuelle Comets, Christelle Rodrigues, Vincent Jullien, Moreno Ursino
article
Pharmaceutical Research, 2021, 38 (6), pp.1057-1066. ⟨10.1007/s11095-021-03052-6⟩
titre
Bayesian Approaches for Confirmatory Trials in Rare Diseases: Opportunities and Challenges
auteur
Moreno Ursino, Nigel Stallard
article
International Journal of Environmental Research and Public Health, 2021, 18 (3), pp.1022. ⟨10.3390/ijerph18031022⟩
titre
An adaptive power prior for sequential clinical trials – Application to bridging studies
auteur
Adrien Ollier, Satoshi Morita, Moreno Ursino, Sarah Zohar
article
Statistical Methods in Medical Research, 2019, pp.096228021988660. ⟨10.1177/0962280219886609⟩
titre
Integration of elicited expert information via a power prior in Bayesian variable selection: Application to colon cancer data
auteur
Sandrine Boulet, Moreno Ursino, Peter F Thall, Bruno Landi, Céline Lepere, Simon Pernot, Anita Burgun, Julien Taïeb, Aziz Zaanan, Sarah Zohar, Anne-Sophie Jannot
article
Statistical Methods in Medical Research, 2020, 38 (12), Ahead of print. ⟨10.1177/0962280219841082⟩
titre
Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies
auteur
Caroline Petit, Adeline Samson, Satoshi Morita, Moreno Ursino, Vincent Jullien, Emmanuelle Comets, Sarah Zohar
article
Statistical Methods in Medical Research, 2018, 27 (6), pp.1860-1877. ⟨10.1177/0962280216671348⟩
titre
L’équipe-projet HeKA
auteur
Adrien Coulet, Stéphanie Allassonniere, François Angoulvant, Anita Burgun, Xiaoyi Chen, David Drummond, Nicolas Garcelon, Anne-Sophie Jannot, Sandrine Katsahian, Antoine Neuraz, Bastien Rance, Brigitte Sabatier, Rosy Tsopra, Moreno Ursino, Sarah Zohar
article
Bulletin de l’Association Française pour l’Intelligence Artificielle, 2021, 112, pp.29-32
titre
Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia
auteur
Claire Dupuis, Lila Bouadma, Etienne de Montmollin, Dany Goldgran-Toledano, Carole Schwebel, Jean Reignier, Mathilde Neuville, Moreno Ursino, Shidasp Siami, Stéphane Ruckly, Corinne Alberti, Bruno Mourvillier, Sébastien Bailly, Kévin Grapin, Virginie Laurent, Niccolo Buetti, Marc Gainnier, Bertrand Souweine, Jean-François Timsit
article
Critical Care Explorations, 2021, 3 (1), pp.e0329. ⟨10.1097/CCE.0000000000000329⟩
titre
An adaptive power prior for sequential clinical trials – Application to bridging studies
auteur
Adrien Ollier, Satoshi Morita, Moreno Ursino, Sarah Zohar
article
Statistical Methods in Medical Research, 2020, 29 (8), pp.2282-2294. ⟨10.1177/0962280219886609⟩
titre
Multistate Modeling of COVID-19 Patients Using a Large Multicentric Prospective Cohort of Critically Ill Patients
auteur
Moreno Ursino, Claire Dupuis, Niccolò Buetti, Etienne de Montmollin, Lila Bouadma, Dany Golgran-Toledano, Stéphane Ruckly, Mathilde Neuville, Yves Cohen, Bruno Mourvillier, Bertrand Souweine, Marc Gainnier, Virginie Laurent, Nicolas Terzi, Shidasp Shiami, Jean Reignier, Corinne Alberti, Jean-François Timsit
article
Journal of Clinical Medicine, 2021, 10 (3), pp.544. ⟨10.3390/jcm10030544⟩
titre
An adaptive power prior for sequential clinical trials – Application to bridging studies
auteur
Adrien Ollier, Satoshi Morita, Moreno Ursino, Sarah Zohar
article
Statistical Methods in Medical Research, 2020, 29 (8), pp.2282-2294. ⟨10.1177/0962280219886609⟩
titre
Bayesian framework for multi-source data integration-Application to human extrapolation from preclinical studies
auteur
Sandrine Boulet, Moreno Ursino, Robin Michelet, Linda Bs Aulin, Charlotte Kloft, Emmanuelle Comets, Sarah Zohar
article
Statistical Methods in Medical Research, 2024, Statistical Methods in Medical Research, ⟨10.1177/09622802241231493⟩
titre
A Bayesian non-inferiority approach using experts’ margin elicitation – application to the monitoring of safety events
auteur
Camille Aupiais, Corinne Alberti, Thomas Schmitz, Olivier Baud, Moreno Ursino, Sarah Zohar
article
BMC Medical Research Methodology, 2019, 19 (1), pp.187. ⟨10.1186/s12874-019-0826-5⟩
titre
Using dichotomized survival data to construct a prior distribution for a Bayesian seamless Phase II/III clinical trial
auteur
Benjamin Duputel, Nigel Stallard, François Montestruc, Sarah Zohar, Moreno Ursino
article
Statistical Methods in Medical Research, 2023, 32 (5), pp.963-977. ⟨10.1177/09622802231160554⟩
titre
DICE: A Bayesian model for early dose finding in phase I trials with multiple treatment courses
auteur
Moreno Ursino, Lucie Biard, Sylvie Chevret
article
Biometrical Journal, In press, ⟨10.1002/bimj.202000369⟩
titre
Bayesian sequential integration within a preclinical pharmacokinetic and pharmacodynamic modeling framework: Lessons learned
auteur
Fabiola La Gamba, Tom Jacobs, Helena Geys, Thomas Jaki, Jan Serroyen, Moreno Ursino, Alberto Russu, Christel Faes
article
Pharmaceutical Statistics, 2019, pst.1941. ⟨10.1002/pst.1941⟩
titre
Bayesian dose‐regimen assessment in early phase oncology incorporating pharmacokinetics and pharmacodynamics
auteur
Emma Gerard, Sarah Zohar, Hoai‐thu Thai, Christelle Lorenzato, Marie‐karelle Riviere, Moreno Ursino
article
Biometrics, 2022, ⟨10.1111/biom.13433⟩
titre
Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial
auteur
Maëva Cotinat, Isabelle Boquet, Moreno Ursino, Cécile Brocard, Elisabeth Jouve, Corinne Alberti, Laurent Bensoussan, Jean-Michel Viton, Frédéric Brocard, Olivier Blin
article
PLoS ONE, 2023, 18, ⟨10.1371/journal.pone.0276892⟩
titre
Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study
auteur
Olga Solovyeva, Munyaradzi Dimairo, Christopher Weir, Siew Wan Hee, Aude Espinasse, Moreno Ursino, Dhrusti Patel, Andrew Kightley, Sarah Hughes, Thomas Jaki, Adrian Mander, Thomas Evans, Shing Lee, Sally Hopewell, Khadija Rerhou Rantell, An-Wen Chan, Alun Bedding, Richard Stephens, Dawn Richards, Lesley Roberts, John Kirkpatrick, Johann de Bono, Christina Yap
article
BMC Medicine, 2023, 21 (1), pp.246. ⟨10.1186/s12916-023-02937-0⟩
titre
Meta‐analyses of phase I dose‐finding studies: Application for the development of protein kinase inhibitors in oncology
auteur
Laura Caquelin, Pauline Badra, Lucas Poulain, Bruno Laviolle, Moreno Ursino, Clara Locher
article
Research Synthesis Methods, 2024, ⟨10.1002/jrsm.1747⟩
titre
Approaches to sample size calculation for clinical trials in rare diseases
auteur
Tim Friede, Corinne Alberti, Norbert Benda, Emmanuelle Comets, Alex Dmitrienko, Alexandra Graf, Burak Kürsad Günhan, Frederike Lentz, Thomas Ondra, Christian Röver, Artemis Toumazi, Steffen Unkel, Moreno Ursino, Gernot Wassmer, Frank Miller, Sarah Zohar, Nigel Stallard, Jason Madan, Martin Posch, Siew Wan Hee, Michael Pearce, Mårten Vågerö, Simon Day
article
Pharmaceutical Statistics, 2018, 17 (3), pp.214-230. ⟨10.1002/pst.1848⟩
titre
Postoperative analgesia after surgical repair of distal radius fracture: a randomized comparison between distal peripheral nerve blockade and surgical site infiltration
auteur
Didier Sciard, Kailai Xu, Anne Soulier, Guillaume Dufour, Moreno Ursino, Corinne Alberti, Marc Beaussier
article
Minerva Anestesiologica, 2023, 89 (10), ⟨10.23736/s0375-9393.23.16956-2⟩
titre
A dose finding design for seizure reduction in neonates
auteur
Moreno Ursino, Ying Yuan, Corinne Alberti, Emmanuelle Comets, Geraldine Favrais, Tim Friede, Frederike Lentz, Nigel Stallard, Sarah Zohar
article
Journal of the Royal Statistical Society: Series C Applied Statistics, 2019, 68 (2), pp.427-444. ⟨10.1111/rssc.12289⟩
titre
Bayesian knowledge integration for an in vitro–in vivo correlation model
auteur
Elvira Erhardt, Moreno Ursino, Jeike Biewenga, Tom Jacobs, Mauro Gasparini
article
Biometrical Journal, 2019, 61 (5), pp.1104-1119. ⟨10.1002/bimj.201700263⟩
titre
Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations
auteur
Moreno Ursino, Sarah Zohar, Frederike Lentz, Corinne Alberti, Tim Friede, Nigel Stallard, Emmanuelle Comets
article
Biometrical Journal, 2017, 59 (4), pp.804-825. ⟨10.1002/bimj.201600084⟩


 

 

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