Séminaire Inriabcd: 7 mai 2019 à 11h00

Of bites and bytes: Tooth development in silico.

Roland Zimm, ENS Lyon

Animal development integrates gene regulatory dynamics, biomechanics and cell behaviours, in usually non-linear and reciprocally interdependent ways. In order to comprehend this complexity, numerical simulations of development are becoming an increasingly important tool. We use two different numerical modelling approaches to understand the developmental underpinnings of tooth shape diversity in sharks, between species, between different individuals as well as within individuals. In particular, we are interested in the contribution of the biomechanical microenvironment surrounding the developing tooth bud to the fine-tuning of tooth shape.

7 man 2019, 11h00, 4e étage